The 45-year-old Maleficent star has three children adopted by her ex-husband and Oscar-winning actor Brad Pitt.
They are Maddox Chivan, 18, Pax Thien, 16, and Zahara Marley, 15.
Brad and Angelina also have three biological children: daughter Shiloh, 14, and 11-year-old twins, Knox and Vivienne.
Her eldest son Maddox comes from Cambodia, while Pax is from Vietnam, and Zahara is from Ethiopia.
Angelina said: "The important thing is to talk openly about all of this and share it with others. 'Adoption' and 'Orphanage' are positive words in our home.
" With my adopted children, I can't talk about pregnancy, but I talk in great detail and love about the journey I made to find them, about how it felt to see them for the first time. . "
The actress also talked about what adoptive parents owe to their children when the background is so different from theirs.
Angelina added: â?? All adopted children come with a beautiful mystery of a world that is meeting your world. "
" When they are from another race and foreign land, that mystery, that gift, is so complementary ."
" They should never lose touch with where they came from. They have roots that you don't have. Honor them. Learn from them. It's the most amazing way to share with others. "
She concluded: " They are not entering your world, you are entering each other's worlds. "
Jolie had been in a relationship with Brad Pitt since 2005 before they eventually married in 2014.
Their marriage ended two years later, in 2016, when they separated, and Angelina filed for divorce before sharing custody of their children.
She was previously married to actor Johnny Lee Miller from 1996 to 1999, before marrying actor Billy Bob Thornton from 2000 to 2003.
